A child is the greatest blessing

Overview

IUI is the process of placing processed semen samples containing motile sperms through the cervix into the uterine cavity around the time of ovulation.

IUI is low risk compared to other more invasive fertility treatments like IVF. Some of the risks of IUI are:

  • Multiple births: You might release more than one egg if you take fertility medication. This increases your chances of becoming pregnant with twins, triplets or more. A pregnancy with multiple babies carries a higher risk of premature labour and low birth weight.
  • Infection: This is rare.
  • Spotting: The procedure can cause a small amount of vaginal bleeding.
  • Ovarian hyperstimulation syndrome (OHSS): A rare side effect caused by taking too much fertility medication. OHSS causes your ovaries to become painful and swollen.

IUI Procedure

You will generally be advised medications (oral tablets and/or gonadotropin injections) from day 2 or 3 of your menses for 5-10 days. Your response will be monitored by sonography every 3-4 days.

When the follicle/s are of appropriate size, the final process of ovulation will be triggered with an injection of hCG and the IUI procedure will be planned approximately 36 hours later.

Your partner needs to provide his semen sample on the day of an IUI. If a problem is anticipated, the previously preserved sample can also be used. The semen sample is processed in the laboratory and then injected into the uterus.

You may then be given medications for support for the next 14 days at the end of which a serum beta-hCG test is done to confirm pregnancy.

Why is IUI performed?

People choose IUI for many reasons, such as infertility issues, or as a reproductive option for same-sex female couples or females who wish to have a baby without a partner, using a sperm donor.

Intrauterine insemination (IUI) may be used when these conditions are present:

  • Cervical mucus problems or other problems with your cervix. Your cervix separates your vagina and uterus from each other. Mucus produced by your cervix helps sperm travel from your vagina, through your uterus and to your fallopian tubes. Thick mucus can make it hard for sperm to swim. With IUI, sperm bypasses your cervix and goes directly to your uterus.
  • Low sperm count or other sperm impairments. Semen analysis is part of infertility treatment. It may show that your partner’s sperm is small, weak, slow or oddly shaped, or that your partner doesn’t have much sperm. IUI can help these problems because only high-quality sperm is selected and used in your treatment.
  • Youre using donor sperm. IUI is used when people use sperm from a person who isn’t the birth parent’s partner. This is called donor insemination (DI). DI is done when one partner has no sperm or when the sperm quality is so low that the sperm can’t be used. Single women or same-sex female couples who wish to conceive can also use donor sperm.
  • Ejaculation or erection dysfunction. IUI can be used when one partner can’t get or sustain an erection or isn’t able to ejaculate.
  • Semen allergy. In rare cases, people have an allergy to their partner’s semen. It can cause burning, swelling and redness in their vagina. IUI can be effective because the proteins causing the allergy are removed during sperm washing.
  • Unexplained infertility. This is when healthcare providers can’t find the cause of infertility.

FAQ’s

The procedure is not painful as it is done under light sedation, but may cause mild discomfort. At our clinic, we use mild anesthesia administered through an IV route which relieves discomfort.

IVF is likely to be recommended for the following fertility problems:
1. If you have blocked or damaged fallopian tubes
2. If your partner has male infertility issues like Oligozoospermia, Teratozoospermia or Athenozoospermia.
3. If you have premature ovarian failure
4. If you have been trying to conceive for at least two years and a cause hasn’t been found to explain why you have not become pregnant.

1. Women with a tubal problem
2. Women with unexplained fertility
3. Women with severe endometriosis
4. Couples with male factor infertility

Before treatment start, you will discussmedical history and the treatment processincluding risk and side effects kith your doctor.
1. Stimulation- After your baseline scans, injections will stimulate your ovaries to develop multiple eggs
2. Monitoring- Regular scans and blood test allow us to monitor your ovanan response to the drug
3. Trigger injections- When hormones are at the right levels another injection will trigger the eggs to mature
4. Egg collection and sperm collection- Eggs are collected via a needle passed through the vagina whilst you are under sedation. A semen sample is required on the day of egg collection
5. Fertilization and embryo development- Eggs and sperm are placed P an incubator to fertilize. Embryo development is monitored by CRGH embryologist
6. Embryo transfer- The best ennbryo(s) 6 /are transferred back into the uterus. Any suitable embryo not transferred can be frozen for Later use
7. Pregnancy test- Patient takes a pregnancy test 16 days after embryo transfer. At this stage we will arrange appropriate support.

So the point is that the IVF success rate could vary based on the denominator used to calculate the IVF cycle outcome. Its always preferable to always define the success rate using all the available denominators and discuss every one of them with the couple. The couple should be able to understand the sucess chances for their particular condition. There are even more denominators like age, number of embryos transfered, frozen or fresh emebto transfer, ICSI, PGD / PGS tested embryos etc. This further gets complicated when each ivf clinic or ivf doctor in the center wants to boos their success rates to showcase themselves in this highly competitive era.

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